Vacatures geplaatst door Erasmus MC

Mimir verzorgt het geautomatiseerde beheer van vacatures op vacaturebanken voor Erasmus MC.

Laatste vacatures

Ambtelijk secretaris Medisch Ethische Toetsingscommissie (METC) met specialisme Biobank onderzoek

Als ambtelijk secretaris ben je het eerste aanspreekpunt op het gebied van de toetsing van Biobank onderzoek. Daarnaast draai je mee in de toetsing van de lokale uitvoerbaarheid, niet WMO-plichtig onderzoek (inclusief Biobank onderzoek) en de WMO toetsing.

Je werkzaamheden bestaan uit de inhoudelijke en beleidsmatige ondersteuning van de commissie. Daarbij kun je denken aan het inhoudelijk voorbereiden en faciliteren van stukken voor Biobank onderzoek ter goedkeuring van de commissie, het bewaken van de naleving van procedures volgens wettelijke en interne voorschriften, het bijhouden van relevante ontwikkelingen en een bijdrage leveren aan de implementatie in het Erasmus MC van nieuwe wet- en regelgeving vooral op het gebied van Biobank onderzoek. Je onderhoudt contact met commissieleden, onderzoekers en externe instellingen ten aanzien van de verschillende aspecten voor toetsing van medisch-wetenschappelijk onderzoek, adviseert onderzoekers op het gebied van Biobank onderzoek en participeert in regionale en landelijke netwerken op het gebied van toetsing van Biobank onderzoek.

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20-09-2019 Erasmus MC
PhD student - In vivo imaging of orthotopic tumor models, imaging and interaction with hyperthermia

The Department of Molecular Genetics is looking for a highly motivated PhD student with a strong background in biomedical technology and/or small animal in vivo imaging. The department studies the molecular mechanisms of multicomponent biological pathways within the DNA damage response. INTO-PROT is a 4-year collaborative research project aiming at further improving proton therapy of cancer funded by a Dutch Cancer Society Consortium grant. The project aims to define the therapeutic efficacy of proton versus photon irradiation and identify any proton-combination treatments for head and neck cancer that are superior to photon irradiation.

Within the INTO-PROT project you will make use of X-ray CT and fluorescence based molecular tomography yielding complementary information on both anatomy and biological activity of the tumor. Quantitative analysis of these data will be set up to take full advantage of the acquired information and to study spatiotemporal changes with high sensitivity, accuracy, and reproducibility. To this end we will develop novel image analysis techniques for automatic image alignment, detection and segmentation of relevant image structures, and quantitative measurements of the spatial and temporal properties of these structures.

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20-09-2019 Erasmus MC
Clinical PhD Student for Q-Maestro: Improving Stroke Treatment by Advanced Analysis of Digital Subtraction Angiography Images

Ischemic stroke is a worldwide major cause of death and permanent disability. Several recent RCTs have shown that patient outcome in acute stroke caused by an occlusion of a large vessel could be dramatically improved by intra-arterial treatment in which the occluding thrombus is mechanically removed from the occluded vessel. Imaging during these endovascular interventions is highly relevant for therapeutic decision making as it guides the interventionist during the procedure However, in addition to this anatomical information these images may provide additional information on perfusion of the affected brain tissue. Knowledge on how this perfusion data relates to clinical outcome, and technology to obtain objective quantitative perfusion data from intervention DSA images, however, is currently virtually lacking.

This project therefore aims to develop and assess methods to quantify (microvascular) perfusion in Digital Subtraction Angiography (DSA) images during endovascular treatment for acute ischemic stroke. For this, we are currently looking for two PhD students: one with a clinical background and one with a background in an engineering field. They will co-work on this project: the engineering PhD will work on image processing approaches (traditional and/or AI-based) to extract relevant information from clinical DSA images, whereas the clinical PhD will focus on investigating associations between DSA-derived perfusion parameters and clinical data such as patient outcome and endovascular techniques. This vacancy is for the clinical PhD.

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17-09-2019 Erasmus MC
Engineering PhD Student for Q-Maestro: Improving Stroke Treatment by Advanced Analysis of Digital Subtraction Angiography Images

Ischemic stroke is a worldwide major cause of death and permanent disability. Several recent RCTs have shown that patient outcome in acute stroke caused by an occlusion of a large vessel could be dramatically improved by intra-arterial treatment in which the occluding thrombus is mechanically removed from the occluded vessel. Imaging during these endovascular interventions is highly relevant for therapeutic decision making as it guides the interventionist during the procedure. However, in addition to this anatomical information these images may provide additional information on perfusion of the affected brain tissue. Knowledge on how this perfusion data relates to clinical outcome, and technology to obtain objective quantitative perfusion data from intervention DSA images, however, is currently virtually lacking.

This project therefore aims to develop and assess methods to quantify (microvascular) perfusion in Digital Subtraction Angiography (DSA) images during endovascular treatment for acute ischemic stroke. For this, we are currently looking for two PhD students: one with a clinical background and one with a background in an engineering field. They will co-work on this project: the engineering PhD will work on image processing approaches (traditional and/or AI-based) to extract relevant information from clinical DSA images, whereas the clinical PhD will focus on investigating associations between DSA-derived perfusion parameters and clinical data such as patient outcome and endovascular techniques. This vacancy is for the engineering PhD.

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17-09-2019 Erasmus MC
PhD student on vascular signature mapping of brain tumours

This work focuses on the development of MRI techniques to establish the so-called vascular signature of primary brain tumours. Primary brain tumour, most commonly glioma, is a devastating disease which in adults is generally fatal. The optimal timing of treatment, including surgery, is in part determined by the expected tumour biological behaviour. An important influencer of tumour growth is its vascularisation. While typically assessed with an invasive test taking a tissue sample, vascularisation characteristics can be observed with MRI. However, with the currently available technology this can only be achieved with unacceptably long scan times. In this project, we aim to enhance MRI to gather a large set of quantitative vascularisation parameters within an acceptable scan time from patients with a brain tumour in a clinical setting. The ultimate aim is to improve diagnosis and eventually also the treatment outcome. As a PhD student on this project, you will develop new advanced MRI methods to characterise the vascularisation of brain tumours. The project will use clinical 3T MRI scanners at Erasmus MC and a 7 Tesla MRI scanner in Leiden University Medical Center (LUMC), as part of the collaboration with the Gorter-Centre (Prof. Van Osch).

45 sollicitaties
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11-09-2019 Erasmus MC